Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis

Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis

Systemic mastocytosis (SM) is a hematologic neoplasm with abnormal accumulation of mast cells in various organ systems such as the bone marrow, other visceral organs and skin. So far, only little is known about epigenetic changes contributing to the pathogenesis of SM. In the current article, we pro...

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Bibliographic Details
Main Authors: Edyta Reszka, Ewa Jabłońska, Edyta Wieczorek, Peter Valent, Michel Arock, Gunnar Nilsson, Bogusław Nedoszytko, Marek Niedoszytko
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
mastocytosis
epigenetics
DNA methylation
demethylating agents
<i>DNMT3A</i>
<i>TET2</i>
Online Access:https://www.mdpi.com/1422-0067/22/6/2964

Internet

https://www.mdpi.com/1422-0067/22/6/2964

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