The MXL-3/SBP-1 Axis Is Responsible for Glucose-Dependent Fat Accumulation in C. elegans

The MXL-3/SBP-1 Axis Is Responsible for Glucose-Dependent Fat Accumulation in C. elegans

Chronic exposure to elevated glucose levels leads to fatty acid accumulation, which promotes the development of metabolic diseases such as obesity and type 2 diabetes. MXL-3 is a conserved transcriptional factor that modulates the inhibition of lipolysis in Caenorhabditis elegans. However, the role...

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Bibliographic Details
Main Authors: Fanny Mejia-Martinez, Berenice Franco-Juarez, Elizabeth Moreno-Arriola, Alain Hernández-Vázquez, Marco Martinez-Avila, Saul Gómez-Manzo, Jaime Marcial-Quino, Karla Carvajal, Antonio Velazquez-Arellano, Daniel Ortega-Cuellar
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Genes
Subjects:
Caenorhabditis elegans
glucose
fatty acid
energy metabolism
transcription factor
energy sensor
Online Access:https://www.mdpi.com/2073-4425/8/11/307

Internet

https://www.mdpi.com/2073-4425/8/11/307

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