Heat-killed Trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunity.

Chagas heart disease, caused by the protozoan parasite Trypanosoma cruzi, is a potentially fatal cardiomyopathy often associated with cardiac autoimmunity. T. cruzi infection induces the development of autoimmunity to a number of antigens via molecular mimicry and other mechanisms, but the genesis a...

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Bibliographic Details
Main Authors: Kevin M Bonney, Joann M Taylor, Melvin D Daniels, Conrad L Epting, David M Engman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3024973?pdf=render