Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy.

<h4>Background</h4>Despite guidelines establishing the need to perform comprehensive paediatric drug development programs, pivotal trials in children with epilepsy have been completed mostly in Phase IV as a postapproval replication of adult data. However, it has been shown that the trea...

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Bibliographic Details
Main Authors: Sylvain Rheims, Michel Cucherat, Alexis Arzimanoglou, Philippe Ryvlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18700812/?tool=EBI