Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts

Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts

Calorie restriction (CR) inhibits prostate cancer progression, partially through modulation of the IGF axis. IGF-1 receptor (IGF-1R) blockade reduces prostate cancer xenograft growth. We hypothesized that combining calorie restriction with IGF-1R blockade would have an additive effect on prostate ca...

Full description

Bibliographic Details
Main Authors: Colette Galet, Ashley Gray, Jonathan W. Said, Brandon Castor, Junxiang Wan, Pedro J. Beltran, Franck J. Calzone, David Elashoff, Pinchas Cohen, William J. Aronson
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:International Journal of Molecular Sciences
Subjects:
prostate cancer
calorie restriction
IGF-1R blockade
Online Access:http://www.mdpi.com/1422-0067/14/7/13782

Internet

http://www.mdpi.com/1422-0067/14/7/13782

Similar Items