Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage

Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage

Abstract Background Macroautophagy (hereafter referred to as autophagy) is an evolutionarily conserved intracellular mechanism for lysosomal degradation of damaged cellular components. The specific degradation of nuclear components by the autophagy pathway is called nucleophagy. Most studies have fo...

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Bibliographic Details
Main Authors: Yunong Li, Xiuxing Jiang, Yanhao Zhang, Ziyi Gao, Yanxia Liu, Jinjiao Hu, Xiaoye Hu, Lirong Li, Jingshan Shi, Ning Gao
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Nucleophagy
UBC9
SUMOylation
Lamin A/C
LC3
Online Access:http://link.springer.com/article/10.1186/s13046-019-1048-8

Internet

http://link.springer.com/article/10.1186/s13046-019-1048-8

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