Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function

Psychotropic Drugs Show Anticancer Activity by Disrupting Mitochondrial and Lysosomal Function

Background and Purpose: Drug repositioning is a promising strategy for discovering new therapeutic strategies for cancer therapy. We investigated psychotropic drugs for their antitumor activity because of several epidemiological studies reporting lower cancer incidence in individuals receiving long...

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Bibliographic Details
Main Authors: Marco Varalda, Annamaria Antona, Valentina Bettio, Konkonika Roy, Ajay Vachamaram, Vaibhav Yellenki, Alberto Massarotti, Gianluca Baldanzi, Daniela Capello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
lysosomotropism
cationic amphiphilic drugs (CADs)
autophagy
psychotropic drug
cancer
repositioning
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.562196/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.562196/full

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