Trichostatin A promotes esophageal squamous cell carcinoma cell migration and EMT through BRD4/ERK1/2‐dependent pathway

Abstract Background Histone deacetylases (HDACs) have been demonstrated to be aberrantly activated in tumorigenesis and cancer development. Thus, HDAC inhibitors (HDACIs) are considered to be promising anti‐cancer therapeutics. However, recent studies have shown that HDACIs promote the migration of...

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Bibliographic Details
Main Authors: Danhui Liu, Yuzhen Liu, Bo Qi, Chengwei Gu, Shuhua Huo, Baosheng Zhao
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Cancer Medicine
Subjects:
EMT
Online Access:https://doi.org/10.1002/cam4.4059