Differential protein distribution between the nucleus and mitochondria: implications in aging

The coordination of nuclear and mitochondrial genomes plays a pivotal role in maintenance of mitochondrial biogenesis and functionality during stress and aging. Environmental and cellular inputs signal to nucleus and/or mitochondria to trigger interorganellar compensatory responses. Loss of this tig...

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Bibliographic Details
Main Authors: Eirini Lionaki, Ilias Gkikas, Nektarios Tavernarakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00162/full