Exosomes and autophagy: coordinated mechanisms for the maintenance of cellular fitness

Exosomes and autophagy: coordinated mechanisms for the maintenance of cellular fitness

Conditions resulting from loss of cellular homeostasis; including oxidative stress, inflammation, protein aggregation, endoplasmic reticulum stress, metabolic stress and perturbation of mitochondrial function, are common to many pathological disorders and contribute to aging. Cells face these stress...

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Bibliographic Details
Main Authors: Francesc eBaixauli, Carlos eLopez-Otin, Maria eMittelbrunn
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Immunology
Subjects:
Autophagy
Exosomes
Multivesicular Bodies
neurodegeneration
proteostasis
endosome
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00403/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00403/full

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