SNPs within CHRNA5-A3-B4 and CYP2A6/B6, nicotine metabolite concentrations and nicotine dependence treatment success in smokers

SNPs within CHRNA5-A3-B4 and CYP2A6/B6, nicotine metabolite concentrations and nicotine dependence treatment success in smokers

Aim. Plasma values of nicotine and its metabolites are highly variable, and this variability has a strong genetic influence. In our study, we analysed the impact of common polymorphisms associated with smoking on the plasma values of nicotine, nicotine metabolites and their ratios and investigated t...

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Bibliographic Details
Main Authors: Jaroslav A. Hubacek, Ivana Kurcova, Vera Maresova, Alexandra Pankova, Lenka Stepankova, Kamila Zvolska, Vera Lanska, Eva Kralikova
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2021-03-01
Series:Biomedical Papers
Subjects:
nicotine-acetylcholine receptors
egln2
cyp2a6/b6
tobacco dependence
smoking
cotinine
hydroxycotinine
intensive treatment
nicotine metabolism
Online Access:https://biomed.papers.upol.cz/artkey/bio-202101-0013_snps-within-chrna5-a3-b4-and-cyp2a6-b6-nicotine-metabolite-concentrations-and-nicotine-dependence-treatment-su.php

Internet

https://biomed.papers.upol.cz/artkey/bio-202101-0013_snps-within-chrna5-a3-b4-and-cyp2a6-b6-nicotine-metabolite-concentrations-and-nicotine-dependence-treatment-su.php

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