Progress in Drug Delivery to the Central Nervous System by the Prodrug Approach

Progress in Drug Delivery to the Central Nervous System by the Prodrug Approach

This review describes specific strategies for targeting to the central nervoussystem (CNS). Systemically administered drugs can reach the brain by crossing one of twophysiological barriers resistant to free diffusion of most molecules from blood to CNS: theendothelial blood-brain barrier or the epit...

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Bibliographic Details
Main Authors: Silvia Vertuani, Stefano Manfredini, Carla Biondi, Nunzia Ciliberti, Alessandro Dalpiaz, Barbara Pavan
Format: Article
Language:English
Published: MDPI AG 2008-05-01
Series:Molecules
Subjects:
Brain delivery
nasal administration
prodrugs
SVCT2
carrier-mediated transport
Online Access:http://www.mdpi.com/1420-3049/13/5/1035/

Internet

http://www.mdpi.com/1420-3049/13/5/1035/

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