VOLTAGE-SENSITIVE K+ CHANNELS INHIBIT PARASYMPATHETIC GANGLION TRANSMISSION AND VAGAL CONTROL OF HEART RATE IN HYPERTENSIVE RATS

VOLTAGE-SENSITIVE K+ CHANNELS INHIBIT PARASYMPATHETIC GANGLION TRANSMISSION AND VAGAL CONTROL OF HEART RATE IN HYPERTENSIVE RATS

Parasympathetic withdrawal plays an important role in the autonomic dysfunctions in hypertension. Since hyperpolarizing, voltage-sensitive K+ channels (KV) hamper transmitter release, elevated KV-activity may explain the disturbed vagal control of heart rate (HR) in hypertension. Here, the KV inhibi...

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Bibliographic Details
Main Author: Torill eBerg
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Neurology
Subjects:
Heart Rate
Hypertension
Quinidine
norepinephrine release
Acetylcholine release
Sympathetic ganglia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00260/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00260/full

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