A rapid high-resolution method for resolving DNA topoisomers

Abstract Objective Agarose gel electrophoresis has been the mainstay technique for the analysis of DNA samples of moderate size. In addition to separating linear DNA molecules, it can also resolve different topological forms of plasmid DNAs, an application useful for the analysis of the reactions of...

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Bibliographic Details
Main Authors: Lesley A. Mitchenall, Rachel E. Hipkin, Michael M. Piperakis, Nicolas P. Burton, Anthony Maxwell
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-018-3147-6