Sildenafil Inhibits Myelin Expression and Myelination of Oligodendroglial Precursor Cells
Phosphodiesterases (PDEs) have previously been implicated in oligodendrocyte maturation and myelination of central nervous system axons. Sildenafil citrate is a phosphodiesterase inhibitor known to block PDE5, which also reduces inflammation in the experimental autoimmune encephalomyelitis demyelina...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-03-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1177/1759091419832444 |