Mechanisms of oral absorption improvement for insoluble drugs by the combination of phospholipid complex and SNEDDS

In the present study, a water insoluble drug named silybin was encapsulated into self-nanoemulsifying drug delivery system (SNEDDS) following the preparation of silybin–phospholipid complex (SB–PC), then several methods were carried out to characterize SB–PC–SNEDDS and elucidate its mechanisms to im...

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Bibliographic Details
Main Authors: Yingpeng Tong, Qin Zhang, Wen Shi, Jianxin Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2019.1686086