Embryo-toxicity of docosahexaenoic and eicosapentaenoic acids: In vivo and in silico investigations using the chick embryo model

Objective: The objective of the current study was to evaluate the embryo-toxicity of omega-3 fatty acids. Methods: Firstly, the embryo-toxicity of docosahexaenoic (DHA) and eicosapentaenoic acids (EPA), as well as their interaction with Bcl-2 family members, were predicted using an in silico assay....

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Main Authors: Zohreh Salari, Hadi Tavakkoli, Ahmad Khosravi, Elahe Karamad, Ehsan Salarkia, Mehdi Ansari, Shahriar Dabiri, Abbas Mortazaeizdeh, Seyedeh Saedeh Mosallanejad, Fatemeh Sharifi
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221000032