Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines

Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines

Abstract Background Meningioma tumors arise in arachnoid membranes, and are the most reported central nervous system (CNS) tumors worldwide. Up to 20% of grade I meningioma tumors reoccur and currently predictive cancer stem cells (CSCs) markers for aggressive and drug resistant meningiomas are scar...

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Bibliographic Details
Main Authors: Ishaq Khan, Saleh Baeesa, Mohammed Bangash, Hans-Juergen Schulten, Fahad Alghamdi, Hanadi Qashqari, Nawal Madkhali, Angel Carracedo, Mohamad Saka, Awatif Jamal, Jaudah Al-Maghrabi, Mohammed AlQahtani, Saleh Al-Karim, Ghazi Damanhouri, Kulvinder Saini, Adeel Chaudhary, Adel Abuzenadah, Deema Hussein
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Cancer Cell International
Subjects:
Meningioma
Cancer stem cells
Caspase 3
Nestin
Ki67
CD133
Online Access:http://link.springer.com/article/10.1186/s12935-017-0441-7

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http://link.springer.com/article/10.1186/s12935-017-0441-7

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