The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

<p>Abstract</p> <p>Background</p> <p>The variability of maternal serum biochemical markers for Down syndrome, free β-hCG and PAPP-A can have a different impact on false-positive rates between the 10+0 and 13+6 week of gestation. The study population comprised 2883 unaff...

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Bibliographic Details
Main Authors: Kos Milan, Sabolović-Rudman Senka, Šimundić Ana-Maria, Zec Ivana, Tišlarić-Medenjak Dubravka, Megla Željka
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/3/194