Features of bilirubin-induced reactive microglia: From phagocytosis to inflammation

Features of bilirubin-induced reactive microglia: From phagocytosis to inflammation

Microglia constitute the brain's immunocompetent cells and are intricately implicated in numerous inflammatory processes included in neonatal brain injury. In addition, clearance of tissue debris by microglia is essential for tissue homeostasis and may have a neuroprotective outcome. Since unco...

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Bibliographic Details
Main Authors: Sandra L. Silva, Ana R. Vaz, Andreia Barateiro, Ana S. Falcão, Adelaide Fernandes, Maria A. Brito, Rui F.M. Silva, Dora Brites
Format: Article
Language:English
Published: Elsevier 2010-12-01
Series:Neurobiology of Disease
Subjects:
Microglial activation
Phagocytic activity
Inflammatory signalling pathways
Mitogen activated protein kinases
Nuclear factor-κB
Hyperbilirubinemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110002664

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http://www.sciencedirect.com/science/article/pii/S0969996110002664

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