Acid-base equilibria of 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid and its labeling with technetium-99m

The acid-base equilibria of a novel hepatobiliary imaging agent, 2,4-diiodo-6-methylphenylcarbamoylmethyl iminodiacetic acid (DIIODIDA) were studied. The potentiometrically determined acidity constants of the second carboxylic group, amino and amide groups were pK2 = 2.52 ± 0.02; pK3 = 5.86 ± 0.06 a...

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Bibliographic Details
Main Authors: Brborić Jasmina S., Jovanović Mirjana S., Popović Gordana V., Kapetanović Vera P., Vladimirov Sote M.
Format: Article
Language:English
Published: Serbian Chemical Society 2006-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2006/0352-51390601055B.pdf