Construction of a High-Resolution Physical Map of the ∼ 1-Mb Region of Human Chromosome 7q31.1–q31.2 Harboring a Putative Tumor Suppressor Gene

Construction of a High-Resolution Physical Map of the ∼ 1-Mb Region of Human Chromosome 7q31.1–q31.2 Harboring a Putative Tumor Suppressor Gene

Reports of frequent loss of heterozygosity (LOH) of markers on human chromosome 7q in malignant myeloid disorders as well as breast, prostate, ovarian, colon, head and neck, gastric, pancreatic, and renal cell carcinomas suggest the presence of a tumor suppressor gene (TSG). Functional assays have...

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Bibliographic Details
Main Authors: Jean C. Zenklusen, Lauren A. Weintraub, Eric D. Green
Format: Article
Language:English
Published: Elsevier 1999-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
tumor suppressor gene
human chromosome 7
physical mapping
expressed-sequence tag
bacterial artificial chromosome
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800311

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http://www.sciencedirect.com/science/article/pii/S1476558699800311

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