A comparison of rpoB and 16S rRNA as markers in pyrosequencing studies of bacterial diversity.

<h4>Background</h4>The 16S rRNA gene is the gold standard in molecular surveys of bacterial and archaeal diversity, but it has the disadvantages that it is often multiple-copy, has little resolution below the species level and cannot be readily interpreted in an evolutionary framework. W...

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Bibliographic Details
Main Authors: Michiel Vos, Christopher Quince, Agata S Pijl, Mattias de Hollander, George A Kowalchuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22355318/pdf/?tool=EBI