Long-chain acylcarnitines regulate the hERG channel.

In some pathological conditions carnitine concentration is high while in others it is low. In both cases,cardiac arrhythmias can occur and lead to sudden cardiac death. It has been proposed that in ischaemia, acylcarnitine (acyl-CAR), but not carnitine, is involved in arrhythmias through modulation...

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Bibliographic Details
Main Authors: Fabio Ferro, Aude Ouillé, Truong-An Tran, Pierre Fontanaud, Patrick Bois, Dominique Babuty, François Labarthe, Jean-Yves Le Guennec
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3404973?pdf=render