Breast Cancer Resistance Protein (BCRP/<i>ABCG2</i>) Inhibits Extra Villous Trophoblast Migration: The Impact of Bacterial and Viral Infection

Breast Cancer Resistance Protein (BCRP/<i>ABCG2</i>) Inhibits Extra Villous Trophoblast Migration: The Impact of Bacterial and Viral Infection

Extravillous trophoblasts (EVT) migration into the decidua is critical for establishing placental perfusion and when dysregulated, may lead to pre-eclampsia (PE) and intrauterine growth restriction (IUGR). The breast cancer resistance protein (BCRP; encoded by <i>ABCG2</i>) regulates the...

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Bibliographic Details
Main Authors: Phetcharawan Lye, Enrrico Bloise, Lubna Nadeem, Chun Peng, William Gibb, Tania M. Ortiga-Carvalho, Stephen J. Lye, Stephen G. Matthews
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
breast cancer resistance protein (bcrp/<i>abcg2</i>)
extra villous trophoblast
first trimester placenta
migration
infection
Online Access:https://www.mdpi.com/2073-4409/8/10/1150

Internet

https://www.mdpi.com/2073-4409/8/10/1150

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