Vitamin D supplementation improves SIRT1, Irisin, and glucose indices in overweight or obese type 2 diabetic patients: a double-blind randomized placebo-controlled clinical trial

Vitamin D supplementation improves SIRT1, Irisin, and glucose indices in overweight or obese type 2 diabetic patients: a double-blind randomized placebo-controlled clinical trial

Abstract Background Vitamin D (VD) may increase sirtuin 1 (SIRT1) and subsequently PPAR-γ coactivator 1α (PGC-1α) and irisin levels and these improvements may reduce insulin resistance (IR). The aim was to assess the effects of vitamin D supplementation on SIRT1, irisin, and IR in overweight/obese t...

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Bibliographic Details
Main Authors: Peivasteh Safarpour, Milad Daneshi-Maskooni, Mohammadreza Vafa, Mitra Nourbakhsh, Leila Janani, Mohsen Maddah, Fatemeh-Sadat Amiri, Fereshteh Mohammadi, Homa Sadeghi
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Family Practice
Subjects:
Vitamin D
SIRT1
Irisin
Glucose indices, type 2 diabetes
Overweight/obesity
Online Access:https://doi.org/10.1186/s12875-020-1096-3

Internet

https://doi.org/10.1186/s12875-020-1096-3

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