A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY)

A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY)

Abstract Background Fresh frozen plasma (FFP) is the accepted standard treatment for clotting factor replacement in bleeding patients during or immediately after cardiac surgery. In the United Kingdom prothrombin complex concentrate (PCC) is not licensed in this setting, although it is being used in...

Full description

Bibliographic Details
Main Authors: Laura Green, Neil Roberts, Jackie Cooper, Jane Field, Ravi Gill, Andrew Klein, Seema Agarwal, Simon Stanworth, Atholl Johnston, Vivienne Monk, Ben O’Brien
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Trials
Subjects:
Cardiac surgery
Bleeding
Fresh frozen plasma
Prothrombin complex concentrate
Randomised controlled trial
Pilot study
Online Access:https://doi.org/10.1186/s13063-019-3759-8

Internet

https://doi.org/10.1186/s13063-019-3759-8

Similar Items