Mycobacterium smegmatis HtrA Blocks the Toxic Activity of a Putative Cell Wall Amidase

Summary: Mycobacterium tuberculosis, the causative agent of tuberculosis, withstands diverse environmental stresses in the host. The periplasmic protease HtrA is required only to survive extreme conditions in most bacteria but is predicted to be essential for normal growth in mycobacteria. We confir...

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Bibliographic Details
Main Authors: Katherine J. Wu, Cara C. Boutte, Thomas R. Ioerger, Eric J. Rubin
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718320084