Inhibition of the Heat Shock Protein A (HSPA) Family Potentiates the Anticancer Effects of Manumycin A

Manumycin A (MA) is a well-tolerated natural antibiotic showing pleiotropic anticancer effects in various preclinical in vitro and in vivo models. Anticancer drugs may themselves act as stressors to induce the cellular adaptive mechanism that can minimize their cytotoxicity. Heat shock proteins (HSP...

Full description

Bibliographic Details
Main Authors: Damian Robert Sojka, Sylwia Hasterok, Natalia Vydra, Agnieszka Toma-Jonik, Anna Wieczorek, Agnieszka Gogler-Pigłowska, Dorota Scieglinska
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/6/1418