Engineering large, anatomically shaped osteochondral constructs with robust interfacial shear properties

Abstract Despite the prevalence of large (>5 cm2) articular cartilage defects involving underlying bone, current tissue-engineered therapies only address small defects. Tissue-engineered, anatomically shaped, native-like implants may address the need for off-the-shelf, tissue-repairing therapies...

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Bibliographic Details
Main Authors: Wendy E. Brown, Brian J. Huang, Jerry C. Hu, Kyriacos A. Athanasiou
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00152-0