Suppression of osteogenic differentiation and mitochondrial function change in human periodontal ligament stem cells by melatonin at physiological levels
N-Acetyl-5-methoxytryptamine (melatonin, MT) at pharmacological concentrations promotes the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells; however, its role at physiological concentrations (1 pM–10 nM) remains unclear. We explored the effects of 1 pM–1 µM MT on the o...
Main Authors: | Miaomiao Zheng, Fuping Zhang, Wenguo Fan, Liulin Jiang, Jingzhou Li, Shanshan Xie, Fang Huang, Hongwen He |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/8663.pdf |
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