T-Cells and Interferon Gamma Are Necessary for Survival Following Crimean-Congo Hemorrhagic Fever Virus Infection in Mice

T-Cells and Interferon Gamma Are Necessary for Survival Following Crimean-Congo Hemorrhagic Fever Virus Infection in Mice

Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne febrile illness with wide geographic distribution. In humans, the disease follows infection by the Crimean-Congo hemorrhagic fever virus (CCHFV) and begins as flu-like symptoms that can rapidly progress to hemorrhaging and death. Case fat...

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Bibliographic Details
Main Authors: David W. Hawman, Kimberly Meade-White, Shanna Leventhal, Aaron Carmody, Elaine Haddock, Kim Hasenkrug, Heinz Feldmann
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Microorganisms
Subjects:
Crimean-Congo hemorrhagic fever
CCHFV
T-cells
mouse model
IFNγ
Online Access:https://www.mdpi.com/2076-2607/9/2/279

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https://www.mdpi.com/2076-2607/9/2/279

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