Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone

Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone

Primary cilia are evolutionary conserved microtubule-based organelles that protrude from the surface of most mammalian cells. Phosphoinositides (PI) are membrane-associated signaling lipids that regulate numerous cellular events via the recruitment of lipid-binding effectors. The temporal and spatia...

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Bibliographic Details
Main Authors: Sarah E. Conduit, Elizabeth M. Davies, Alex J. Fulcher, Viola Oorschot, Christina A. Mitchell
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
primary cilia
transition zone
INPP5E
phosphoinositides
superresolution microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.634649/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.634649/full

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