Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients

Local eosinophils are associated with increased IgA subclass levels in the sinonasal mucosa of chronic rhinosinusitis with polyp patients

Abstract Background Chronic rhinosinusitis (CRS) describes an inflammatory condition affecting the sinonasal mucosa. As the immune system players such as immunoglobulins play prominent roles in the development of CRS, we aimed to investigate the expression of IgA subclasses and factors involved in I...

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Bibliographic Details
Main Authors: Hossein Aazami, Farhad Seif, Babak Ghalehbaghi, Pegah Babaheidarian, Alireza Mohebbi, Aslan Ahmadi, Majid Khoshmirsafa, Sahand Ghalehbaghi, Babak Behnam, Kobra Zinat Entezami, Zahra Madjd, Reza Falak
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
CRSsNP
CRSwNP
B cell
IgA
Class switching
Nasal polyps
Online Access:http://link.springer.com/article/10.1186/s13223-020-00428-y

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http://link.springer.com/article/10.1186/s13223-020-00428-y

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