Like Iron in the Blood of the People: The Requirement for Heme Trafficking in Iron Metabolism

Heme is an iron-containing porphyrin ring that serves as a prosthetic group in proteins that function in diverse metabolic pathways. Heme is also a major source of bioavailable iron in the human diet. While the synthesis of heme has been well-characterized, the pathways for heme trafficking remain p...

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Bibliographic Details
Main Authors: Iqbal eHamza, Tamara eKorolnek
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00126/full