Chemokine Receptor-6 Promotes B-1 Cell Trafficking to Perivascular Adipose Tissue, Local IgM Production and Atheroprotection

Chemokine Receptor-6 Promotes B-1 Cell Trafficking to Perivascular Adipose Tissue, Local IgM Production and Atheroprotection

Chemokine receptor-6 (CCR6) mediates immune cell recruitment to inflammatory sites and has cell type-specific effects on diet-induced atherosclerosis in mice. Previously we showed that loss of CCR6 in B cells resulted in loss of B cell-mediated atheroprotection, although the B cell subtype mediating...

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Bibliographic Details
Main Authors: Prasad Srikakulapu, Aditi Upadhye, Fabrizio Drago, Heather M. Perry, Sai Vineela Bontha, Chantel McSkimming, Melissa A. Marshall, Angela M. Taylor, Coleen A. McNamara
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
B-1 cells
IgM
CCR6
atherosclerosis
inflammation
perivascular adipose tissue
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.636013/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.636013/full

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