IL1RL1 gene variants and nasopharyngeal IL1RL-a levels are associated with severe RSV bronchiolitis: a multicenter cohort study.

Targets for intervention are required for respiratory syncytial virus (RSV) bronchiolitis, a common disease during infancy for which no effective treatment exists. Clinical and genetic studies indicate that IL1RL1 plays an important role in the development and exacerbations of asthma. Human IL1RL1 e...

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Bibliographic Details
Main Authors: Tina E Faber, Annemieke Schuurhof, Annelies Vonk, Gerard H Koppelman, Marije P Hennus, Jan L L Kimpen, Riny Janssen, Louis J Bont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3344820?pdf=render