Efficacy and safety of human soluble thrombomodulin (ART-123) for treatment of patients in France with sepsis-associated coagulopathy: post hoc analysis of SCARLET

Efficacy and safety of human soluble thrombomodulin (ART-123) for treatment of patients in France with sepsis-associated coagulopathy: post hoc analysis of SCARLET

Abstract Background The phase 3 multinational SCARLET study evaluated the efficacy and safety of a recombinant human soluble thrombomodulin (ART-123) for treatment of sepsis-associated coagulopathy (SAC), which correlates with increased mortality risk in patients with sepsis. Although no significant...

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Bibliographic Details
Main Authors: Bruno François, Maud Fiancette, Julie Helms, Emmanuelle Mercier, Jean-Baptiste Lascarrou, Toshihiko Kayanoki, Kosuke Tanaka, David Fineberg, Jean-Louis Vincent, Xavier Wittebole
Format: Article
Language:English
Published: SpringerOpen 2021-03-01
Series:Annals of Intensive Care
Subjects:
Sepsis
Sepsis-associated coagulopathy
Thrombomodulin
ART-123
Heparin
France
Online Access:https://doi.org/10.1186/s13613-021-00842-4

Internet

https://doi.org/10.1186/s13613-021-00842-4

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