Utility of Network Integrity Methods in Therapeutic Target Identification

Analysis of the biological gene networks involved in a disease may lead to the identification of therapeutic targets. It requires exploring network properties, particularly, the importance of individual genes. There are many measures that consider the importance of nodes in a network and some may s...

Full description

Bibliographic Details
Main Authors: Qian ePeng, Nicholas eSchork
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00012/full