Biomarkers that currently effect clinical practice in lung cancer: EGFR, ALK, MET, ROS-1 and KRAS

Lung cancer remains the most lethal malignancy in the world. Despite improvements in surgical treatment, systemic therapy and radiotherapy, the 5-year survival rate for all patients diagnosed with lung cancer remains between 15-20%. Newer therapeutic strategies rely on specific molecular alterations...

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Bibliographic Details
Main Authors: Grzegorz Janusz Korpanty, Donna Marie Graham, Mark eVincent, Natasha B. Leighl
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Oncology
Subjects:
Met
ALK
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00204/full