Targeted Suppression of Chaperone-Mediated Autophagy by miR-320a Promotes α-Synuclein Aggregation
Chaperone-mediated autophagy (CMA) is involved in wild-type α-synuclein degradation in Parkinson’s disease (PD), and LAMP2A and Hsc 70 have recently been indicated to be deregulated by microRNAs. To recognize the regularory role of miR-320a in CMA and the possible role in α-synuclein degradation, in...
Main Authors: | Guobin Li, Haiying Yang, Dezhang Zhu, Hui Huang, Guoyuan Liu, Peng Lun |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/15/9/15845 |
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