The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies

The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies

Inflammatory cell invasion and cytokine activation are important steps in the pathogenesis of immune-mediated diseases of muscle. Metalloproteinase-disintegrins (ADAMs) are considered to play a critical role in leukocyte migration by promoting cellular adhesion, cleavage of molecules of the extracel...

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Bibliographic Details
Main Authors: Thomas Dehmel, Angela Janke, Hans-Peter Hartung, Hans-Hilmar Goebel, Heinz Wiendl, Bernd C. Kieseier
Format: Article
Language:English
Published: Elsevier 2007-03-01
Series:Neurobiology of Disease
Subjects:
Myositis
Immunology
Matrix metalloproteinases
Autoimmune disease
T lymphocytes
Macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106003020

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http://www.sciencedirect.com/science/article/pii/S0969996106003020

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