Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes

Stromal interaction molecule 1 (STIM1) is a ubiquitously expressed Ca<sup>2+</sup> sensor protein that induces permeation of Orai Ca<sup>2+</sup> channels upon endoplasmic reticulum Ca<sup>2+</sup>-store depletion. A drop in luminal Ca<sup>2+</sup> cau...

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Bibliographic Details
Main Authors: Matthias Sallinger, Adéla Tiffner, Tony Schmidt, Daniel Bonhenry, Linda Waldherr, Irene Frischauf, Victoria Lunz, Isabella Derler, Romana Schober, Rainer Schindl
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/12/4410