Rat Chondrocyte Inflammation and Osteoarthritis Are Ameliorated by Madecassoside

As a joint disease, osteoarthritis (OA) is caused by the breakdown of subchondral bone and cartilage damage. Inflammatory factors, such as interleukin- (IL-) 1β, mediate the progression of OA. Madecassoside (MA), a triterpenoid component derived from the gotu kola herb (Centella asiatica), exhibits...

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Bibliographic Details
Main Authors: Safwat Adel Abdo Moqbel, Yuzhe He, Langhai Xu, Chiyuan Ma, Jisheng Ran, Kai Xu, Lidong Wu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/7540197