ZEB1 protects skeletal muscle from damage and is required for its regeneration

Following muscle damage, an inflammatory response is associated to activation of satellite cells, which drive muscle repair. Here, the authors show that upregulation of Zeb1 in macrophages and muscle fibres regulates inflammation, and also show a role for Zeb1 in maintenance of satellite cell quiesc...

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Bibliographic Details
Main Authors: Laura Siles, Chiara Ninfali, Marlies Cortés, Douglas S. Darling, Antonio Postigo
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08983-8