Prognostic Significance of RAS Mutations and P53 Expression in Cutaneous Squamous Cell Carcinomas

Prognostic Significance of RAS Mutations and P53 Expression in Cutaneous Squamous Cell Carcinomas

<i>TP53</i> is considered the most commonly-altered gene in cutaneous squamous cell carcinoma (cSCC). Conversely, <i>RAS</i> mutations have been reported in a low percentage of cSCC. The objective of our study was to evaluate the frequency of p53 expression and <i>RAS&l...

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Bibliographic Details
Main Authors: Manuel António Campos, Sofia Macedo, Margarida Sá Fernandes, Ana Pestana, Joana Pardal, Rui Batista, João Vinagre, Agostinho Sanches, Armando Baptista, José Manuel Lopes, Paula Soares
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
<i>RAS</i>
p53
mutation
expression
prognostic biomarker
prognosis
Online Access:https://www.mdpi.com/2073-4425/11/7/751

Internet

https://www.mdpi.com/2073-4425/11/7/751

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