A pivotal role for Interferon-α receptor-1 in neuronal injury induced by HIV-1

Abstract Background HIV-1 infection remains a major public health concern despite effective combination antiretroviral therapy (cART). The virus enters the central nervous system (CNS) early in infection and continues to cause HIV-associated neurocognitive disorders (HAND). The pathogenic mechanisms...

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Bibliographic Details
Main Authors: Hina Singh, Daniel Ojeda-Juárez, Ricky Maung, Rohan Shah, Amanda J. Roberts, Marcus Kaul
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-020-01894-2