Recurrent chromosome 22 deletions in osteoblastoma affect inhibitors of the Wnt/beta-catenin signaling pathway.

Osteoblastoma is a bone forming tumor with histological features highly similar to osteoid osteoma; the discrimination between the tumor types is based on size and growth pattern. The vast majority of osteoblastomas are benign but there is a group of so-called aggressive osteoblastomas that can be d...

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Bibliographic Details
Main Authors: Karolin H Nord, Jenny Nilsson, Elsa Arbajian, Fredrik Vult von Steyern, Otte Brosjö, Anne-Marie Cleton-Jansen, Karoly Szuhai, Pancras C W Hogendoorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827481?pdf=render