Nav1.5 cardiac sodium channels, regulation and clinical implications

Voltage-gated sodium channels constitute a group of membrane proteins widely distributed thought the body. In the heart, there are at least six different isoforms, being the Nav1.5 the most abundant. The channel is composed of an α subunit that is formed by four domains of six segments each, and fou...

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Bibliographic Details
Main Authors: Henry Humberto León Ariza, Natalia Valenzuela Faccini, Ariana Carolina Rojas Ortega, Daniel Alfonso Botero Rosas
Format: Article
Language:English
Published: Universidad Nacional de Colombia 2014-10-01
Series:Revista de la Facultad de Medicina
Subjects:
Online Access:https://revistas.unal.edu.co/index.php/revfacmed/article/view/44015