Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies

Site-specific recombinases (SSRs) such as Cre are widely used in gene targeting and genetic approaches for cell labeling and manipulation. They mediate DNA strand exchange between two DNA molecules at dedicated recognition sites. Precise understanding of the Cre recombination mechanism, including th...

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Bibliographic Details
Main Authors: Katherine Chuang, Eileen Nguyen, Yuri Sergeev, Tudor C. Badea
Format: Article
Language:English
Published: Oxford University Press 2016-03-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.115.025841