Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies
Site-specific recombinases (SSRs) such as Cre are widely used in gene targeting and genetic approaches for cell labeling and manipulation. They mediate DNA strand exchange between two DNA molecules at dedicated recognition sites. Precise understanding of the Cre recombination mechanism, including th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2016-03-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.115.025841 |